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Journal of Dermatological Treatment

Journal of Dermatological Treatment

IF: 2.89
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Combination of benzoyl peroxide 5% gel with liquid cleanser and moisturizer SPF 30 in acne treatment results in high levels of subject satisfaction, good adherence and favorable tolerability.

Published:1 February 2018 DOI: 10.1080/09546634.2017.1342758 PMID: 28678647
Mi-Ran Kim, Nabil Kerrouche

Abstract

Background: Skin care products (cleansers and moisturizers) to complement benzoyl peroxide (BPO) in the treatment of acne may improve treatment tolerability and adherence.

Objective: Evaluate subject satisfaction after use of BPO 5% gel in combination with liquid cleanser and moisturizer SPF 30.

Methods: Open-label study including subjects aged ≥12?years with mild-to-moderate facial acne; ClinicalTrials.gov Identifier: NCT02589405. Once daily BPO 5% gel, twice daily liquid cleanser and once daily moisturizer SPF 30 were applied for 12?weeks. Assessments included a subject satisfaction questionnaire, investigator global assessment of improvement, lesion counts, the presence of Propionibacterium acnes, and safety.

Results: Fifty subjects were enrolled. Most subjects were overall satisfied with the three-part regimen (87%) and felt better about themselves (94%). Subjects indicated the skin care products helped prepare the skin for treatment (85%), relieve itchy skin (81%) and reduce irritation (87%). Most subjects considered that the liquid cleanser (80%) and moisturizer SPF 30 (84%) were a necessary part of acne treatment. BPO reduced P. acnes load by 89% at week 1. The treatment was well tolerated.

Conclusions: The combination of BPO 5% gel with liquid cleanser and moisturizer SPF 30 resulted in high levels of subject satisfaction, good tolerability and treatment adherence.

Substances (3)

Related products
Procduct Name CAS Molecular Formula Supplier Price
Benzoyl peroxide 94-36-0 C14H10O4 544 suppliers $22.00-$782.00
PROPIONIBACTERIUMACNES 6 suppliers Inquiry
SPF experimental animal 2 suppliers Inquiry

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