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Journal of Arrhythmia

IF: 2.2
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Adenosine—A drug with myriad utility in the diagnosis and treatment of arrhythmias

Published:18 December 2020 DOI: 10.1002/joa3.12453 PMID: 33664892
Anunay Gupta MD, DM, Yash Lokhandwala MD, DM, Nitish Rai MD, DM, Amit Malviya MD, DM

Abstract

Adenosine has been used in the emergency treatment of arrhythmia for more than nine decades. However, cardiologists are often unfamiliar about its basic mechanism and various diagnostic and therapeutic uses, considering it mainly as a therapeutic drug for supraventricular tachycardia. This article discusses the role of adenosine relevant to emergency physicians, cardiologists, and electrophysiologists. Understanding of the mechanisms of adenosine and its electrophysiological effects is discussed first, followed by dosing, side effects, diagnostic, and therapeutic uses. Finally, the role of adenosine in the electrophysiology laboratory is discussed.

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