價(jià)格 | 詢價(jià) |
包裝 | 1EA |
最小起訂量 | 1EA |
發(fā)貨地 | 湖北 |
更新日期 | 2020-01-16 |
英文名稱:NLRP3 Polyclonal Antibody | |
貨號(hào): PAB38738 | 克隆性: 多克隆 |
規(guī)格: 10 μl / 20 μl / 50 μl / 100 μl |
Product name | NLRP3 Polyclonal Antibody |
Isotype | IgG |
Form | Lyophilized or Liquid |
Tested applications | WB,IF,ELISA |
Species reactivity | Human,Mouse,Rat |
Host Species | Rabbit |
Purity | Affinity purification |
?
Immunogen Information:
? Immunogen | Recombinant protein of human NLRP3 |
Calculated molecular weight | 83kDa/105kDa/111kDa/112kDa/115kDa/118kDa |
Observed molecular weight? | 118kDa |
Swiss Prot | Q96P20 |
Gene ID (NCBI) | 114548 |
Alternative Names | NLRP3; AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; FCAS; FCAS1; FCU; MWS; NALP3; PYPAF1; NLR family pyrin domain containing 3 |
?
Application Notes:
?
WB | 1:200 - 1:1000 |
IF | 1:50 - 1:200 |
? | ? |
??????????? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ??
Western blot analysis of extracts of various cell lines, using NLRP3 antibody. | ? | Immunofluorescence analysis of mouse lung using NLRP3 antibody. |
?
Background:
?This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.?
?
Storage:
? Storage instructions | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
成立日期 | 2014-04-10 (11年) | 注冊(cè)資本 | 500萬人民幣 |
員工人數(shù) | 年?duì)I業(yè)額 | ||
主營行業(yè) | 經(jīng)營模式 |
產(chǎn)品名稱 | 價(jià)格 | 公司名稱 | 報(bào)價(jià)日期 | |
---|---|---|---|---|
¥960.00 |
VIP9年
|
北京索萊寶科技有限公司
|
2024-11-18 | |
¥1098 |
VIP3年
|
上海滬震實(shí)業(yè)有限公司
|
2024-11-18 | |
詢價(jià) |
上海瑤韻生物科技有限公司
|
2024-11-05 |