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NLRP3 Polyclonal Antibody
  • NLRP3 Polyclonal Antibody

NLRP3 Polyclonal Antibody

價(jià)格 詢價(jià)
包裝 1EA
最小起訂量 1EA
發(fā)貨地 湖北
更新日期 2020-01-16

產(chǎn)品詳情

英文名稱:NLRP3 Polyclonal Antibody
貨號(hào): PAB38738克隆性: 多克隆
規(guī)格: 10 μl / 20 μl / 50 μl / 100 μl
2020-01-16 NLRP3 Polyclonal Antibody NLRP3 Polyclonal Antibody 1EA/RMB
Product Information:?

Product name

NLRP3 Polyclonal Antibody

Isotype

IgG

Form

Lyophilized or Liquid

Tested applications

WB,IF,ELISA

Species reactivity

Human,Mouse,Rat

Host Species

Rabbit

Purity

Affinity purification

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Immunogen Information:

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Immunogen

Recombinant protein of human NLRP3

Calculated molecular weight

83kDa/105kDa/111kDa/112kDa/115kDa/118kDa

Observed molecular weight?

118kDa

Swiss Prot

Q96P20

Gene ID (NCBI)

114548

Alternative Names

NLRP3; AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; FCAS; FCAS1; FCU; MWS; NALP3; PYPAF1; NLR family pyrin domain containing 3

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Application Notes:

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WB

1:200 - 1:1000

IF

1:50 - 1:200

? ?

??????????1? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ??2

Western blot analysis of extracts of various cell lines, using NLRP3 antibody.

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Immunofluorescence analysis of mouse lung using NLRP3 antibody.

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Background:

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This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.?

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Storage:

?

Storage instructions

Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

關(guān)鍵字: NLRP3 Polyclonal Antibody;抗體

公司簡介

成立日期 2014-04-10 (11年) 注冊(cè)資本 500萬人民幣
員工人數(shù) 年?duì)I業(yè)額
主營行業(yè) 經(jīng)營模式
  • 武漢華聯(lián)科生物技術(shù)有限公司
非會(huì)員
  • 公司成立:11年
  • 注冊(cè)資本:500萬人民幣
  • 企業(yè)類型:孫建偉
  • 主營產(chǎn)品:
  • 公司地址:湖北省武漢光谷國際生物醫(yī)藥企業(yè)加速器3.1期第25棟南側(cè)4層 郵編:430212
詢盤

NLRP3 Polyclonal Antibody相關(guān)廠家報(bào)價(jià)

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VIP3年
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2024-11-18
詢價(jià)
上海瑤韻生物科技有限公司
2024-11-05
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