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Product name
DPPA4 Polyclonal Antibody
Isotype
IgG
Form
Lyophilized or Liquid
Tested applications
WB,ELISA,IHC
Species reactivity
Human,Mouse,Rat
Host Species
Rabbit
Purity
Affinity purification
Immunogen Information:
Immunogen
Recombinant protein of human DPPA4
Calculated molecular weight
33kDa
Observed molecular weight?
38kDa
Swiss Prot
Q7L190
Gene ID (NCBI)
55211
Alternative Names
2410091M23Rik
Application Notes:
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
1:500 - 1:2000
IHC
1:50 - 1:500
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Western blot analysis of extracts of various cell lines, using DPPA4 antibody.
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Background:
This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
Storage:
Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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