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Anti-CBLN1 Polyclonal Antibody,Anti-CBLN1 Polyclonal Antibody
  • Anti-CBLN1 Polyclonal Antibody,Anti-CBLN1 Polyclonal Antibody

Anti-CBLN1 Polyclonal Antibody

價(jià)格 1600.00 960.00
包裝 100ul 50ul
最小起訂量 50ul
發(fā)貨地 北京
更新日期 2024-11-18
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產(chǎn)品詳情

中文名稱:Anti-CBLN1 Polyclonal Antibody英文名稱:Anti-CBLN1 Polyclonal Antibody
Gene ID: 869Subcellular Locations: Cell membrane Cytoplasm?
Swiss Prot: P23435保存: Store at -20°C. Avoid freeze / thaw cycles.
別名: CER產(chǎn)品編號: K107418P
儲存液: Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.純化方法: Affinity purification
蛋白分子量: 21kDa交叉反應(yīng): Human Mouse Rat
克隆類型: Polyclonal Antibody免疫原: A synthetic peptide of human CBLN1
品牌: Solarbio宿主: Rabbit
稀釋比例: IHC 1:50-200.亞型: IgG
應(yīng)用: IHC英文名稱: Anti-CBLN1 Polyclonal Antibody
2024-11-18 Anti-CBLN1 Polyclonal Antibody Anti-CBLN1 Polyclonal Antibody 100ul/1600.00RMB;50ul/960.00RMB 1600.00

背景資料

"Required for synapse integrity and synaptic plasticity. During cerebellar synapse formation, essential for the matching and maintenance of pre- and post-synaptic elements at parallel fiber-Purkinje cell synapses, the establishment of the proper pattern of climbing fiber-Purkinje cell innervation, and induction of long-term depression at parallel fiber-Purkinje cell synapses. Plays a role as a synaptic organizer that acts bidirectionally on both pre- and post-synaptic components. On the one hand induces accumulation of synaptic vesicles in the pre-synaptic part by binding with NRXN1 and in other hand induces clustering of GRID2 and its associated proteins at the post-synaptic site through association of GRID2. NRXN1-CBLN1-GRID2 complex directly induces parallel fiber protrusions that encapsulate spines of Purkinje cells leading to accumulation of GRID2 and synaptic vesicles. Required for CBLN3 export from the endoplasmic reticulum and secretion (By similarity). NRXN1-CBLN1-GRID2 complex mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis.The cerebellin peptide exerts neuromodulatory functions. Directly stimulates norepinephrine release via the adenylate cyclase/PKA-dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release (By similarity)."
關(guān)鍵字: Anti-CBLN1 Polyclonal Antibody;抗體

公司簡介

北京索萊寶科技有限公司是一家集研發(fā)、生產(chǎn)、銷售、服務(wù)于一體的高科技生物企業(yè)。技術(shù)推廣;技術(shù)轉(zhuǎn)讓;技術(shù)咨詢;技術(shù)服務(wù);生物試劑技術(shù)開發(fā);銷售生物試劑盒、實(shí)驗(yàn)室專用化學(xué)試劑、實(shí)驗(yàn)室專用設(shè)備、辦公用品、化工產(chǎn)品(不含危險(xiǎn)化學(xué)品)、計(jì)算機(jī)軟件及輔助設(shè)備;貨物進(jìn)出口、技術(shù)進(jìn)出口、代理進(jìn)出口;委托加工生產(chǎn)生物制品、生化制品、化工產(chǎn)品(不含危險(xiǎn)化學(xué)品);生產(chǎn)生物試劑盒;批發(fā)第一類醫(yī)療器械、第二類醫(yī)療器械;批發(fā)第三類醫(yī)療器械。
成立日期 2004-09-22 (21年) 注冊資本 1000萬元
員工人數(shù) 50-100人 年?duì)I業(yè)額 ¥ 500萬-1000萬
主營行業(yè) 分析化學(xué),生物化工,化學(xué)試劑,醫(yī)藥原料,儀器耗材 經(jīng)營模式 貿(mào)易,工廠,試劑
  • 北京索萊寶科技有限公司
VIP 9年
  • 公司成立:21年
  • 注冊資本:1000萬元
  • 企業(yè)類型:有限責(zé)任公司
  • 主營產(chǎn)品:tris,甘氨酸,瓊脂粉,潮霉素B,SDS,BSA
  • 公司地址:聯(lián)東U谷景盛南四街85A三層
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