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?AT1R/AGTR1 Antibody
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Cat#：PL0301419
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Isotype:Rabbit Polyclonal IgG
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Immunogen：Peptide derived from human AT1R. ?
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Purification:?Immunogen affinity purified
Storage Buffer:?PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background：
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined.
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Alternate Names：
AG2S; Agtr 1; Agtr1; Agtr1a; AGTR1B; Angiotensin II receptor type 1; Angiotensin II type 1 receptor; AT-1B; AT-1r; AT1; At1a; AT1AR; AT1B; AT1BR; AT2R1; AT2R1A; AT2R1B; HAT1R; Type 1 angiotensin II receptor; AGTR1_HUMAN; Type-1 angiotensin II receptor; Angiotensin II type-1 receptor; AT1R; Ang II; Angiotensin II receptor type 1; Angiotensin II type 1 receptor; Angiotensin receptor 1; Angiotensin receptor 1B; AT 1B; AT1; AT1R.?
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Specificity Reaction：Hu, Mo, Rat, Cow
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Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500
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Storage ：
Store at –20oC for one year. Avoid repeated freeze-thaw cycles. At 4oC for 2-3 weeks after reconstituted.
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This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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