??????Alanine Racemase，中文名為丙氨酸消旋酶，催化L-丙氨酸與D-丙氨酸之間相互轉(zhuǎn)化。本產(chǎn)品為大腸桿菌表達(dá)的丙氨酸消旋酶，并經(jīng)簡單純化獲得的可以確保達(dá)到一定酶活力的粗酶液。
??????由于本產(chǎn)品需新鮮制備，確認(rèn)訂購后約6個工作日才可以發(fā)貨。個別情況首次制備出現(xiàn)問題，發(fā)貨時間會順延。
? ? ? 本產(chǎn)品可以提供十公斤、百公斤乃至噸級的粗酶液，如有需求請聯(lián)系碧云天。
??????This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on amino
acids and derivatives. This enzyme participates in alanine and aspartatemetabolism and D-alanine metabolism. It employs one cofactor, pyridoxal phosphate. At least two compounds, 3-Fluoro-D-alanine and D-Cycloserine are known to inhibit this enzyme.The D-alanine produced by alanine racemase is used for peptidoglycan biosynthesis. Peptidoglycan is found in the cell walls of all bacteria, including many which are harmful to humans. The enzyme is absent in higher eukaryotes but found everywhere in prokaryotes, making alanine racemase a great target for antimicrobial drug development.Alanine racemase can be found in some invertebrates.Bacteria can have one (alr gene) or two alanine racemase genes. Bacterial species with two genes for alanine racemase have one that is continually expressed and one that is inducible, which makes it difficult to target both genes for drug studies. However, knockout studies have shown that without the alr gene being expressed, the bacteria would need an external source of D-alanine in order to survive. Therefore, the alr gene is a feasible target for antimicrobial drugs. This product with the indicated enzyme activity was briefly purified from engineered E.coli.
產(chǎn)品詳細(xì)信息見下表:

包裝清單：

保存條件：
??????-20℃或更低溫度保存，至少1個月有效。
注意事項(xiàng)：
??????由于本產(chǎn)品需新鮮制備，在您確認(rèn)訂購后約6個工作日才能發(fā)貨。個別情況首次制備出現(xiàn)問題，發(fā)貨時間會順延。
??????粗酶液的每次凍融均可能會引起部分失活，所以收到酶液后請根據(jù)需要進(jìn)行分裝，并置于-20℃或更低溫度保存。
??????隨著保存時間的延長，酶活力會有一定程度的下降，收到產(chǎn)品后應(yīng)盡快使用。
??????本產(chǎn)品在生產(chǎn)和保存的過程中可能會有混濁或沉淀產(chǎn)生，融化后混勻即可，不影響正常使用。
??????本產(chǎn)品僅限于專業(yè)人員的科學(xué)研究用，不得用于臨床診斷或治療，不得用于食品或藥品，不得存放于普通住宅內(nèi)。
??????為了您的安全和健康，請穿實(shí)驗(yàn)服并戴一次性手套操作。