中文名稱:羅莎白素 | 英文名稱:Rosamultin |
CAS:88515-58-6 | 品牌: TargetMol |
產(chǎn)地: 美國 | 保存條件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
純度規(guī)格: 99.83% | 產(chǎn)品類別: 抑制劑 |
貨號: T5783 |
名稱 | Rosamultin |
描述 | Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity. |
激酶實(shí)驗(yàn) | A substrate, His-Lys-Ala-ArgVal-Leu-(pNO2-Phe)-Glu-Ala-Nle-Ser-NH2, Inc. For the HIV1 protease assay, the stock solution of the prepared enzyme was diluted. The extracts or compounds(Rosamultin) tested were dissolved in dimethyl sulfoxide (10% in the reaction mixture). A reaction mixture (5 uL) composed of 1 L of 50 uM sodium acetate (pH 5.0), 1 uL of a substrate solution, 1uL of the plant extract or compound solution, and 2 uL of HIV1 protease solution, was stirred, centrifuged, and then incubated at 37℃ for 1 hour in a microtube. A control reaction was performed under the same conditions without plant extract or compounds. The reaction was stopped by heating at 90 ℃ for 1 minute. Thirty-five microliters of autoclaved water was added into the reaction mixture, and an aliquot of 5 uL was analyzed by high-performance liquid chromatography (HPLC). |
體外活性 | 來自R. rugosa根部提取的Rosamultin,在100 microM濃度時(shí),抑制HIV-1蛋白酶的活性達(dá)到53%。 |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 10 mg/mL (15.36 mM) |
關(guān)鍵字 | inhibit | Inhibitor | HIV Protease | Protease | antioxidant | triterpenoid | oxidative stress injury | HIV-1 | Rosamultin |
相關(guān)產(chǎn)品 | L-Cystine | Tenofovir | Valproic Acid | Neohesperidin | Emtricitabine | Lamivudine | 5-Fluorouracil | Decanedioic acid | Dextran sulfate sodium salt (MW 4500-5500) | Stavudine | Kaempferol | Dimethyl fumarate |
相關(guān)庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 | 苗藥化合物庫 | 抗衰老化合物庫 | 中藥單體化合物庫 | 天然產(chǎn)物庫 | 抗病毒中藥單體化合物庫 | 中藥抗炎分子庫 | 抗感染天然產(chǎn)物庫 |
成立日期 | 2013-04-18 (12年) | 注冊資本 | 566.265100萬人民幣 |
員工人數(shù) | 100-500人 | 年?duì)I業(yè)額 | ¥ 1億以上 |
主營行業(yè) | 天然產(chǎn)物,生化試劑,分子生物學(xué),分子砌塊,生物技術(shù)服務(wù) | 經(jīng)營模式 | 貿(mào)易,工廠,試劑,定制,服務(wù) |
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