Product Name：SPACE peptide
CAS No.：1621717-95-0
Synonyms：皮膚穿透肽SPACE peptide
Catalog No.：218P861
Brand：HongTide（上海鴻肽生物）
Description：SPACE peptide是一種皮膚穿透肽，是由11個氨基酸組成的環(huán)狀多肽。SPACE peptide 能增強大分子透明質(zhì)酸的局部傳遞。SPACE 肽與小分子和蛋白質(zhì)等貨物結(jié)合時，能夠促進它們穿過角質(zhì)層進入表皮和真皮.SPACE 肽還表現(xiàn)出對各種細胞的滲透增加，包括角質(zhì)形成細胞、成纖維細胞和內(nèi)皮細胞，可能是通過巨胞飲作用途徑.SPACE 肽通過跨細胞途徑增強環(huán)孢菌素 A 皮膚滲透，通過 SPACE 與角蛋白和環(huán)孢菌素 A 的同時結(jié)合增強其分配到富含角蛋白的角質(zhì)細胞中.
SPACE peptide is a skin penetrating peptide that is a cyclic polypeptide composed of 11 amino acids. SPACE peptide can enhance the local transmission of macromolecular hyaluronic acid. When SPACE peptides bind to small molecules and proteins, they can promote their penetration through the stratum corneum and into the epidermis and dermis SPACE peptides also exhibit increased permeability to various cells, including keratinocytes, fibroblasts, and endothelial cells, possibly through the macrophagocytic pathway SPACE peptide enhances skin penetration of cyclosporin A through a cross cellular pathway, and enhances its distribution to keratin rich keratinocytes by simultaneously binding with keratin and cyclosporin A
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | ACTGSTQHQCG(Disulfide bridge:Cys2-Cys10) |
Sequence(3-letter code) | H-Ala-Cys-Thr-Gly-Ser-Thr-Gln-His-Gln-Cys-Gly-OH(Disulfide bridge：Cys2-Cys10) |
Peptide Structure | 
|
Molecular Formula | C40H63N15O17S2 |
Molecular Weight | 1090.15 |
訂購聯(lián)系方式：
上海鴻肽生物科技有限公司
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郵箱：sales1@hongtide.com
本產(chǎn)品僅供科研使用。
關鍵字： 1621717-95-0;SPACE peptide ;皮膚穿透肽SPACE peptide;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術轉(zhuǎn)讓為主要業(yè) 務科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務為帆，為科研服務”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務及產(chǎn)品。