B7-H5產(chǎn)品信息
英文名稱:V-domain Ig suppressor of T-cell activation
中文名稱:T細(xì)胞活化的免疫球蛋白抑制V型結(jié)構(gòu)域
靶點(diǎn)別稱:B7-H5,SISP1,Gi24,VISTA
物種:Human / Mouse / Rhesus macaque
屬性:Protein
標(biāo)記:Biotin-labeled / Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
>95% as determined by SEC-MALS.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
B7-H5分子背景
血小板受體Gi24,也稱為B7-H5和應(yīng)激誘導(dǎo)分泌蛋白-1(Sisp-1),是一種在人類中由C10orf54基因編碼的蛋白質(zhì),該基因含有1個(gè)Ig樣(免疫球蛋白樣)結(jié)構(gòu)域。至于C10orf54基因,C10orf54似乎與BMP-4呈正相互作用,增強(qiáng)BMP信號(hào)傳導(dǎo)和ESCs從未分化狀態(tài)向分化狀態(tài)的轉(zhuǎn)變。人C10orf54被MT1-MMP進(jìn)行蛋白水解切割,產(chǎn)生可溶性30kDa細(xì)胞外片段和25-30kDa膜結(jié)合片段。
B7-H5用戶評(píng)價(jià)
關(guān)鍵字: B7-H5;B7-H5蛋白;SISP1;SISP1蛋白;B7-H5重組蛋白;
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