IL-12 R beta 1產(chǎn)品信息
英文名稱:Interleukin-12 receptor
中文名稱:白細(xì)胞介素-12受體
靶點(diǎn)別稱:IL-12 R beta 1,IL12RB1,CD212,IL12R,IL12RB,IL-12RB1
物種:Human / Mouse / Cynomolgus
屬性:Protein
標(biāo)記:Biotin-labeled / Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
IL-12 R beta 1分子背景
IL-12R亞基是細(xì)胞因子受體超家族的成員,功能性高親和力IL-12R由至少兩個(gè)β型細(xì)胞因子受體亞基組成,每個(gè)亞基獨(dú)立地對(duì)IL-12表現(xiàn)出低親和力。IL-12 Rβ1(白細(xì)胞介素-12受體亞基β-1)也稱為IL-12RB1、CD212。作為一種白細(xì)胞介素受體,它以低親和力結(jié)合白細(xì)胞介蛋白-12,并參與IL12的轉(zhuǎn)導(dǎo)。它與IL12RB2結(jié)合,形成IL12的功能性高親和力受體。還與IL23R結(jié)合形成白細(xì)胞介素-23受體,該受體可能通過激活Jak-Stat信號(hào)級(jí)聯(lián)在IL23信號(hào)轉(zhuǎn)導(dǎo)中發(fā)揮作用。
IL-12 R beta 1用戶評(píng)價(jià)
關(guān)鍵字: IL12RB1;IL12RB1蛋白;白介素12受體;IL-12 R beta 1;CD212;
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