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IL-15RA產品信息
英文名稱:Interleukin-15 receptor subunit alpha
中文名稱:白細胞介素-15受體α亞基
靶點別稱:IL-15 R alpha,CD215,IL15RA,IL-15RA,IL-15R-alpha
物種:Human / Mouse
屬性:Protein
標記:Biotin-labeled / FITC Labeled / Unconjugated / PE Labeled
內毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
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IL-15RA分子背景
IL15R是IL15RA、IL2RB和IL2RG的異三聚體。IL-15RA,也稱為CD215、IL-15Rα,是一種廣泛表達的60kDa跨膜糖蛋白。白細胞介素-15的高親和力受體??梢皂樖胶头词叫盘?,其中來自一個細胞亞群的IL15R將IL15呈遞給相鄰的IL2RG表達細胞。不同異構體的表達可能會改變或干擾信號轉導。白細胞介素(IL)-15超激動劑/IL-15受體α融合復合物(IL-15SA/IL-15RA;ALT-803)激活CD8 T細胞和NK細胞上的IL-15受體,并顯示出顯著的抗腫瘤作用。信號轉導涉及SYK。與膜結合形式相比,可溶性sIL-15RA形式在所有腦結構中都存在更高水平。
IL-15RA用戶評價
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關鍵字: IL15RA;IL15RA蛋白;白介素15受體;白介素15受體蛋白;CD215;
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