中文名:L-環(huán)絲氨酸
英文名:L-Cycloserine
英文別名:L-Cycloserine|339-72-0|Levcycloserine|(S)-4-Aminoisoxazolidin-3-one|Levcicloserina|Levcycloserinum|(4S)-4-amino-1,2-oxazolidin-3-one|Cyclo-L-serine|(S)-4-Amino-3-isoxazolidone|(S)-4-Amino-3-isoxazolidinone|(S)-(-)-Cycloserine|Cycloserine, l-|(-)-cycloseri
純度:10mM in DMSO
貨號:L423473
包裝:1ml
Cas號:339-72-0
存儲溫度:-80℃儲存
產(chǎn)品介紹:
L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase, which is the first enzyme of the sphingolipid pathway, and causes the synthesis of sphingolipids to decrease. In vitro studies demonstrated that L-cyloserine inhibits 3-ketodihydrosphingosine synthetase 100 times more than D-Cycloserine .Research regarding L-Cycloserine and its effect on the immune response suggest that L-Cycloserine increases the level of IL-4 producing helper T cells and suppress the adhesion molecules CD29 and CD98. L-Cycloserine also inhibits SPTLC (serine palmitoyltransferase (SPT)), and HIV-1 investigations in the CD4+ lymphoid cell line (CEM) have shown that L-Cycloserine can inhibit HIV-1 replication.
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