中文名：硫藤黃素
英文名：Thiolutin
英文別名：Thiolutin|87-11-6|Acetopyrrothin|Acetopyrrothine|NSC3927|N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)acetamide|3-Acetamido-5-methylpyrrolin-4-one(4,3-d)-1,2-dithiole|NSC-3927|Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrr
純度：95%
貨號：T102393
包裝：5mg、1mg、25mg
Cas號：87-11-6
存儲溫度：-20°C儲存
產(chǎn)品介紹：
Thiolutin is an RNA polymerase inhibitor, and a sulfur-based microbial antibiotic generated by Streptomyces sp. The compound has been shown to inhibit transcription in Saccharomyces cerevisiae and mRNA degradation. Thiolutin inhibits the adhesion of endothelial cells, including adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin, and restricts tumor cell-induced angiogenesis. Studies have reported that Thiolutin is an effective inducer of HSP 27 (heat shock protein 27; Hsp27) phosphorylation. Research shows that in the presence of Thiolutin, the interaction between Hsp27 and nestin is disrupted, which results in the breakdown of nestin filaments.An RNA polymerase inhibitor and suppressor of tumor cell-induced angiogenesis
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關鍵字： Thiolutin;87-11-6;Acetopyrrothin;Acetopyrrothine
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