中文名：N-羥基-N'-苯基辛二酰胺
英文名：Vorinostat (SAHA, MK0683)
中文別名：SAHA|異羥肟酸|N-羥基-N'-苯基辛二酰胺|伏立諾他|MK0683|辛二酰苯胺異羥肟酸
英文別名：Vorinostat|149647-78-9|SAHA|suberoylanilide hydroxamic acid|Zolinza|N-hydroxy-N'-phenyloctanediamide|N1-hydroxy-N8-phenyloctanediamide|Suberanilohydroxamic acid|MK-0683|MK0683|Octanediamide, N-hydroxy-N'-phenyl-|Vorinostat (SAHA, MK0683)|N'-hydroxy-N-phen
純度：≥99.0%
貨號(hào)：V125336
包裝：100mg、500mg、250mg
Cas號(hào)：149647-78-9
存儲(chǔ)溫度：-20°C儲(chǔ)存
產(chǎn)品介紹：
Suberoylanilide Hydroxamic Acid (SAHA) is a potent histone deacetylase (HDAC) inhibitor that has been shown to inhibit proliferation and cause cell cycle arrest at G1. Experiments suggest that SAHA also causes morphological changes, such as enlargement and flattening of the cytoplasm, resulting in growth inhibition. Treatment of cells with SAHA also decreases the expression of anti-apoptosis proteins Bcl-xL and survivin.
A potent HDAC inhibitor; also causes cell cycle arrest at G1
SAHA可用于研究基因調(diào)控、轉(zhuǎn)錄調(diào)控和細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)。
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關(guān)鍵字： SAHA;異羥肟酸;N-羥基-N'-苯基辛二酰胺;伏立諾他
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