中文名：SANT-1,平滑刺猬信號拮抗劑

英文名：SANT-1

英文別名：SANT-1|304909-07-7|1-Piperazinamine, N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-|CHEMBL515916|N-(4-benzylpiperazin-1-yl)-1-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methanimine|(E)-N-(4-BENZYLPIPERAZIN-1-YL)-1-(3,5-DIMETHYL-1-PHENY

純度：≥98%

貨號：S129830

包裝：100mg、25mg、5mg

Cas號：304909-07-7

存儲溫度：-20°C儲存

產(chǎn)品介紹：

SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist effects with IC50 of 20 nM.Treatment of Anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma cells2 and chronic lymphocytic leukemia cells3 with SANT-1 induced cell death.

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