中文名:KW-2449,抑制FLT3,ABL和Aurora激酶
英文名:KW-2449
英文別名:KW-2449|1000669-72-6|KW 2449|KW2449|841258-76-2|(E)-(4-(2-(1H-indazol-3-yl)vinyl)phenyl)(piperazin-1-yl)methanone|[4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone|CHEMBL1908397|2D9N67F58G|Methanone, [4-[2-(1H-indazol-3-yl)ethenyl]phenyl]
純度:≥98%
貨號(hào):K127169
包裝:100mg、25mg、5mg
Cas號(hào):1000669-72-6
存儲(chǔ)溫度:-20°C儲(chǔ)存
產(chǎn)品介紹:
KW-2449能較強(qiáng)地抑制Flt3,IC50為6.6 nM,對(duì)FGFR1,Bcr-Abl和Aurora A的抑制性適中,而對(duì) PDGFRβ,IGF-1R,EGFR則無(wú)抑制性。A multikinase inhibitor of FLT3, ABL, ABL-T315I, and Aurora kinase。
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