中文名：鹽酸法舒地爾
英文名：Fasudil Hydrochloride
中文別名：鹽酸法舒地爾|5-(1-高哌嗪)磺酰基異喹啉鹽酸鹽|(5-異喹啉磺?；?高哌嗪鹽酸鹽
英文別名：Fasudil hydrochloride|105628-07-7|Fasudil HCl|Eril|Fasudil (HA-1077) HCl|5-((1,4-Diazepan-1-yl)sulfonyl)isoquinoline hydrochloride|Fasudil (Hydrochloride)|AT-877|Fasudil Monohydrochloride|ha-1077|SQ04N8S7BR|Fasudil, Monohydrochloride Salt|DTXSID1045615|MF
純度：98%
貨號：F122336
包裝：100mg、500mg、250mg
Cas號：105628-07-7
存儲溫度：避光,-20°C儲存
產(chǎn)品介紹：
Fasudil, Monohydrochloride Salt is a cell-permeable, selective ROCK inhibitor which induces neuroprotection in vitro. Studies sμggest that when acting as a ROCK inhibitor, Fasudil reduces neutrophil transendothelial migration by diminishing cytoskeletal rearrangement of endothelial cells. In addition, Fasudil significantly protects against MeHg-induced axonal degeneration and apoptotic cell death in cultured cortical neurons. Alternate studies show that Fasudil plays an important role in osteoblastic differentiation of stromal cells via increasing the mRNA expression of collagen-I, osteocalcin, and bone morphogenetic protein-2 (BMP-2). Furthermore, noggin, a BMP-2 antagonist can reverse the effects of Fasudil induced mRNA expression of collagen-I and osteocalcin. Upon inhibition of Rho-kinase, Fasudil significantly stimulates FGF-2-induced accumulation of vascular endothelial growth factor (VEGF). Fasudil, Monohydrochloride Salt is an inhibitor of cGKI, MSK1, PKA, PRK2, Rock-2, AMPK, CaMKII, Polycystin-1 and Rsk-1.A selective ROCK inhibitor
查看阿拉丁官網(wǎng)此產(chǎn)品相關對應頁面：https://www.aladdin-e.com/zh_cn/F122336.html
關鍵字： 鹽酸法舒地爾;5-(1-高哌嗪)磺?；愢}酸鹽;(5-異喹啉磺?；?高哌嗪鹽酸鹽;Fasudil hydrochloride
上海阿拉丁生化科技股份有限公司是A股上市公司（（股票代碼：688179），專注于科研試劑的研發(fā)、生產(chǎn)和銷售，已陸續(xù)建立多個工廠和研發(fā)中心。作為領軍企業(yè)，阿拉丁始終堅持質量第一，連續(xù)13年被評為“最受歡迎試劑品牌”。
阿拉丁目前常備庫存試劑產(chǎn)品品種超過7萬種，SKU總數(shù)超過46萬，產(chǎn)品線涵蓋了化學試劑、生化試劑、藥靶配體、蛋白質和抗體等多個領域，是國內少數(shù)化學試劑到生物試劑全面發(fā)展的國產(chǎn)試劑品牌，產(chǎn)品同步發(fā)布在我們國內（www.aladdin-e.com）和海外（www.aladdinsci.com）電商平臺。