Mouse Anti-P53 Monoclonal Antibody
DATASHEET
Host:Mouse
Target Protein:P53
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:7157
Swiss Prot:P04637
Source:KLH conjugated synthetic peptide derived from human p53:
Purification:affinity purified by Protein G
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
Cross Reactive Species:Human
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僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： P53;Widespread p53;Wtp53;Antigen NY-CO-13;Cellular tumor antig;Cys 51 Stop;HGNC11998;P53_HUMAN;
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