Rabbit Anti-phospho-IRE1a (Ser 726) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-IRE1a (Ser 726)
IR:Immunogen Range:SF(p-S)RR
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2081
Swiss Prot:O75460
Source:KLH conjugated synthesised phosphopeptide derived from human IRE1a around the phosphorylation site of Ser726 :SF(p-S)RR
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1ug/test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： phospho-IRE1a (Ser 7;p-IRE1a (phospho-Ser;IRE1 (phospho S726) ;IRE1 alpha (p-Ser726;ERN1;hIRE1p; Inositol requiring ;ERN1_HUMAN;
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