Rabbit Anti-MMP8 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:MMP8
IR:Immunogen Range:241-340/467
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4317
Swiss Prot:P22894
Source:KLH conjugated synthetic peptide derived from human MMP8:241-340/467
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： MMP8;Matrilysin/matrix me;CLG1;Collagenase II;Collagenase 2;Collagenase neutroph;HNC;MMP8_HUMAN;
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