Host:Rabbit
Target Protein:Leptin receptor
IR:Immunogen Range:101-180/262
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3953
Swiss Prot:P48357
Source:KLH conjugated synthetic peptide derived from human Leptin receptor:101-180/262
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(2ug/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Horse
Sheep
Goat
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： obl;CD295;CD 295;HuB219;LEPR;LEP R;LEPROT;Obr;
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