ANTI-TNF RECEPTOR II抗體

價格	詢價
包裝	50ul

最小起訂量	50ul
發(fā)貨地	湖北
更新日期	2024-10-19

產(chǎn)品詳情

中文名稱:ANTI-TNF RECEPTOR II抗體

產(chǎn)品類別: 抗體

Product name：	TNF-R2 Polyclonal Antibody
Alternative Names：	TNFRSF1B; TNFBR; TNFR2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; TNF-RII; TNFR-II; p75; p80 TNF-alpha rec
Applications：	WB,IHC-p,IF,ELISA
Reactivity：	Human,Mouse,Rat
Gene Name：	TNFRSF1B
Protein Name：	Tumor necrosis factor receptor superfamily member 1B
Human Gene Id：	7133
Human Swiss Prot No：	P20333
Mouse Gene Id：	21938
Mouse Swiss Prot No：	P25119
Rat Gene Id：	156767
Rat Swiss Prot No：	Q80WY6
Immunogen：	The antiserum was produced against synthesized peptide derived from human TNF Receptor II. AA range:376-425
Specificity：	TNF-R2 Polyclonal Antibody detects endogenous levels of TNF-R2 protein.
Formulation：	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：	Rabbit
Dilution：	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification：	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：	1 mg/ml
Storage Stability：	-20°C/1 year
MolecularWeight(Da)：	48291
Observed Band(KD)：	48
Background：	TNF receptor superfamily member 1B(TNFRSF1B) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008],
Function：	function:Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.,online information:Clinical information on Enbrel,pharmaceutical:Available under the name Enbrel (Immunex and Wyeth-Ayerst). Used to treat moderate to severe rheumatoid arthritis (RA). Enbrel consist of the extracellular ligand-binding portion of TNFRSF1B linked to an immunoglobulin Fc chain. It binds to TNF-alpha and blocks its interactions with receptors.,PTM:A soluble form (tumor necrosis factor binding protein 2) is produced from the membrane form by
Subcellular Location：	extracellular region,nucleus,plasma membrane,integral component of plasma membrane,integral component of membrane,neuronal cell body,varicosity,membrane raft,perinuclear region of cytoplasm,
Expression：	Muscle,PNS,Urine,

關(guān)鍵字： ANTI-TNF RECEPTOR II;抗體;ANTI-TNF-R2;

公司簡介

ELK Biotechnology位于武漢市東湖新技術(shù)開發(fā)區(qū)，是一家專業(yè)從事生命科學(xué)、免疫研究的高新技術(shù)生物企業(yè)。我們擁有1000平方米的實驗室，擁有獨立的細胞培養(yǎng)室和SPF動物室，專業(yè)從事形態(tài)學(xué)病理學(xué)、細胞生物學(xué)、分子生物學(xué)、蛋白質(zhì)免疫學(xué)、模型動物相關(guān)產(chǎn)品的引進和研發(fā)。公司自成立以來，團隊成員先后參與多項醫(yī)學(xué)生物學(xué)研究項目和國家自然科學(xué)基金項目。并與全國多家企業(yè)和科研機構(gòu)建立合作關(guān)系，為每一位科研人員提供最優(yōu)質(zhì)、最高效的實驗服務(wù)。我們是具有研發(fā)、生產(chǎn)能力的試劑廠商。 ELK Biotechnology專業(yè)生產(chǎn)ELISA試劑盒、抗體及分子生物學(xué)試劑(DNA、RNA提取試劑盒及PCR相關(guān)試劑)。擁有約7000 + ELISA試劑盒、11000 +抗體、50+種分子生物學(xué)試劑及細胞實驗相關(guān)產(chǎn)品。 ELK Biotechnology是可靠的供應(yīng)商，以優(yōu)良的質(zhì)量和有競爭力的價格。我們正在擴展我們的產(chǎn)品線以滿足客戶的需求。每一件產(chǎn)品都經(jīng)過QC平臺的嚴格檢驗，高品質(zhì)得到強有力的保證。我們的目標(biāo)是為科學(xué)家提供最尖端、最具成本效益的研究工具。我們的使命是為全世界的研究人員提供最好的解決方案和最可靠的合作伙伴。

成立日期	2018-02-14 （7年）	注冊資本	300萬(元)
員工人數(shù)	50-100人	年營業(yè)額	￥ 100萬以內(nèi)
主營行業(yè)	生化試劑,抗體,分子生物學(xué),免疫安全	經(jīng)營模式	試劑,定制,服務(wù)

科鹿（武漢）生物科技有限公司

非會員

公司成立：7年
注冊資本：300萬(元)
企業(yè)類型：其他有限責(zé)任公司
主營產(chǎn)品：抗體，細胞，生物試劑等
公司地址：武漢市東湖新技術(shù)開發(fā)區(qū)高新二路388號生物醫(yī)藥園1.2期23號樓

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