Product Name:u-Conotoxin GIIIB
CAS No.:140678-12-2
Synonyms:MU-CONOTOXIN GIIIB;芋螺毒素μ-Conotoxin GIII
Catalog No.:211P09
Brand:HongTide(上海鴻肽生物)
Description:作為由22個氨基酸組成的μ-Conotoxin GIIIB,由于序列中含有三對二硫鍵,因為μ-Conotoxin GIIIB具有二級結(jié)構(gòu)穩(wěn)定、活性高的特點。并且μ-Conotoxin GIIIB能夠特異性地作用于乙酰膽堿受體及其他神經(jīng)遞質(zhì)的各種受體亞型,以及鈣、鈉、鉀等多種離子通道,不僅可直接作為藥物,還可作為理想的分子模板用于發(fā)展新藥先導(dǎo)化合物,對研究神經(jīng)生物學也具有重要意義。
As a compound composed of 22 amino acids μ- Conotoxin GIIIB, due to the presence of three pairs of disulfide bonds in the sequence μ- Conotoxin GIIIB has the characteristics of stable secondary structure and high activity. also μ- Conotoxin GIIIB can specifically act on various receptor subtypes of acetylcholine receptor and other neurotransmitters, as well as a variety of ion channels such as calcium, sodium and potassium. It can not only be directly used as a drug, but also be used as an ideal molecular template for the development of new drug lead compound, which is also of great significance for the research of neurobiology.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | RDCCT-Hyp-Hyp-RKCKDRRCK-Hyp-MKCCA-NH2(Disulfide bonds between Cys3 and Cys15;Cys4 and Cys20;Cys10 and Cys21) |
Sequence(3-letter code) | H-Arg-Asp-Cys-Cys-Thr-Hyp-Hyp-Arg-Lys-Cys-Lys-Asp-Arg-Arg-Cys-Lys-Hyp-Met-Lys-Cys-Cys-Ala-NH2(Disulfide bonds between Cys3 and Cys15;Cys4 and Cys20;Cys10 and Cys21) |
Peptide Structure |
|
Molecular Formula | C101H175N39O30S7 |
Molecular Weight | 2640.17 |
訂購聯(lián)系方式:
上海鴻肽生物科技有限公司
手機: +86-18018095145 (同微信號)
QQ: 3259098395
郵箱:sales1@hongtide.com
關(guān)鍵字: u-Conotoxin GIIIB;140678-12-2;MU-CONOTOXIN GIIIB;芋螺毒素;多肽;
上海鴻肽生物科技有限公司(簡稱:鴻肽生物)是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來,秉持“用質(zhì)量作船, 以服務(wù)為帆,為科研服務(wù)”的企業(yè)理念,為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。