Product Name:ATX-GD-59
CAS No.:N/A
Synonyms:ATX-GD-59 peptide therapy;模仿肽ATX-GD-59
Catalog No.:218P236
Brand:HongTide(上海鴻肽生物)
Description:ATX-GD-59作為藥物多肽,是一種基于肽的療法(peptide therapy),主要生物機(jī)理是模仿抗原表位滅活攻擊甲狀腺的白細(xì)胞,阻止抗促甲狀腺激素受體(TSHR)刺激性抗體的產(chǎn)生,能夠靶向格雷夫斯病的免疫學(xué)基礎(chǔ),有望成為60年來首個(gè)治療格雷夫斯病的修飾創(chuàng)新療法。在臨床上,ATX-GD-59治療格雷夫斯病具有良好的安全性和耐受性,能偶促甲狀腺激素受體(TSHR)抗體水平正常。
As a drug peptide, ATX-GD-59 is a peptide therapy. Its main biological mechanism is to mimic the antigen epitope to inactivate the white blood cells attacking the thyroid, prevent the production of anti thyroid hormone receptor (TSHR) stimulating antibodies, and target the immunological basis of Graves disease. It is expected to become the first modified and innovative therapy for Graves disease in 60 years. In clinical practice, ATX-GD-59 has good safety and tolerance in the treatment of Graves disease, and can even cause the level of thyroid hormone receptor (TSHR) antibody to be normal.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | KKKKYVSIDVTLQQLESHKKK |
Sequence(3-letter code) | H-Lys-Lys-Lys-Lys-Tyr-Val-Ser-Ile-Asp-Val-Thr-Leu-Gln-Gln-Leu-Glu-Ser-His-Lys-Lys-Lys-OH |
Peptide Structure |
|
Molecular Formula | C114H198N32O32 |
Molecular Weight | 2529.26 |
訂購聯(lián)系方式:
上海鴻肽生物科技有限公司
手機(jī): +86-18018095145 (同微信號(hào))
QQ: 3259098395
郵箱:sales1@hongtide.com
關(guān)鍵字: 模仿肽ATX-GD-59;ATX-GD-59;ATX-GD-59 peptide th;多肽;多肽合成;
上海鴻肽生物科技有限公司(簡稱:鴻肽生物)是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來,秉持“用質(zhì)量作船, 以服務(wù)為帆,為科研服務(wù)”的企業(yè)理念,為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。