Host:Rabbit
Target Protein:Cytokeratin 17
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:3872
Swiss Prot:Q04695
Source:Recombinant human Cytokeratin 17 protein (1-100aa):
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
IHC-P(1:50-200)
IHC-F(1:50-200)
Flow-Cyt(1:50)
ICC(1:50)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
本產(chǎn)品僅供科研使用。不能用于人和動物治療等其它臨床診斷使用！
關(guān)鍵字： Keratin17;KRT17;KRT 17;PCHC1;PC2;
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