Product Name:α-Bungarotoxin
CAS No.:11032-79-4
Synonyms:α-銀環(huán)蛇神經(jīng)毒素;α-金環(huán)蛇毒素
Catalog No.:218P214
Brand:HongTide(上海鴻肽生物)
Description:α-Bungarotoxin是來(lái)源于銀環(huán)蛇神經(jīng)毒素屬突觸后神經(jīng)毒素的多肽,序列中含有74個(gè)氨基酸,并且包含四對(duì)二硫鍵,在神經(jīng)-肌肉接頭處與乙酰膽堿競(jìng)爭(zhēng)煙酰胺型乙酰膽堿受體,阻斷乙酰膽堿傳遞的神經(jīng)信號(hào)。作為檢測(cè)乙酰膽堿受體(AchR)的標(biāo)記物;用于AchR純化;研究藥物和受體的相互作用;研究AchR結(jié)構(gòu)與性質(zhì);無(wú)癮性鎮(zhèn)痛、戒毒。
α- Bungarotoxin is a peptide derived from the postsynaptic neurotoxin genus of Bungarus multicinctus neurotoxins, with a sequence of 74 amino acids and four pairs of disulfide bonds. It competes with acetylcholine at the neuromuscular junction for nicotinamide acetylcholine receptors, blocking the neural signals transmitted by acetylcholine. As a marker for detecting acetylcholine receptor (AchR); Used for AchR purification; Study the interaction between drugs and receptors; Study the structure and properties of AchR; Non addictive analgesia and drug withdrawal.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | IVCHTTATSPISAVTCPPGENLCYRKMWCDAFCSSRGKVVELGCAATCPSKKPYEEVTCCSTDKCNPHPKQRPG(Disulfide bridge:3-23, 16-44, 29-33, 48-59, 60-65) |
Sequence(3-letter code) | H-Ile-Val-Cys-His-Thr-Thr-Ala-Thr-Ser-Pro-Ile-Ser-Ala-Val-Thr-Cys-Pro-Pro-Gly-Glu-Asn-Leu-Cys-Tyr-Arg-Lys-Met-Trp-Cys-Asp-Ala-Phe-Cys-Ser-Ser-Arg-Gly-Lys-Val-Val-Glu-Leu-Gly-Cys-Ala-Ala-Thr-Cys-Pro-Ser-Lys-Lys-Pro-Tyr-Glu-Glu-Val-Thr-Cys-Cys-Ser-Thr-Asp-Lys-Cys-Asn-Pro-His-Pro-Lys-Gln-Arg-Pro-Gly-OH(Disulfide bridge:3-23, 16-44, 29-33, 48-59, 60-65) |
Peptide Structure |
|
Molecular Formula | C338H529N97O105S11 |
Molecular Weight | 7984.11 |
訂購(gòu)聯(lián)系方式:
上海鴻肽生物科技有限公司
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關(guān)鍵字: 11032-79-4;α-銀環(huán)蛇神經(jīng)毒素;α-金環(huán)蛇毒素;α-Bungarotoxin;多肽合成;
上海鴻肽生物科技有限公司(簡(jiǎn)稱:鴻肽生物)是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來(lái),秉持“用質(zhì)量作船, 以服務(wù)為帆,為科研服務(wù)”的企業(yè)理念,為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。