11032-79-4
中文名稱
Α-金環(huán)蛇毒
英文名稱
ALPHA-BUNGAROTOXIN
CAS
11032-79-4
分子式
C338H529N97O105S11
分子量
895.082
MOL 文件
11032-79-4.mol
11032-79-4 結(jié)構(gòu)式
基本信息
中文別名
Α-真菌毒素Α-金環(huán)蛇毒
Α-金環(huán)蛇毒
Α-金環(huán)蛇毒素
Α-銀環(huán)蛇神經(jīng)毒素
ALPHA-銀環(huán)蛇神經(jīng)毒素
H-ILE-VAL-CYS-HIS-THR-THR-ALA-THR-SER-PRO-ILE-SER-ALA-VAL-THR-CYS-PRO-PRO-GLY-GLU-ASN-LEU-CYS-TYR-ARG-LYS-MET-TRP-CYS-ASP-ALA-PHE-CYS-SER-SER-ARG-GLY-LYS-VAL-VAL-GLU-LEU-GLY-CYS-ALA-ALA-THR-CYS-PRO-SER-LYS-LYS-PRO-TYR-GLU-GLU-VAL-THR-CYS-CYS-SER-THR-ASP-LYS-CYS-ASN-PRO-HIS-PRO-LYS-GLN-ARG-PRO-GLY-OH
英文別名
α-BuTXALPHA-BGT
ALPHA-BUTX
α-Bungotoxin
A-BUNGAROTOXIN
α-Bungarotoxin
ALPHA-BUNGAROTOXIN
TIANFU-CHEM - ALPHA-BUNGAROTOXIN
M.W. 7984.14 C338H529N97O105S11
BUNGARUS MULTICINCTUS TOXIN, ALPHA
安全數(shù)據(jù)
警示詞警告
危險(xiǎn)性描述H302-H312-H332
WGK Germany3
WGK Germany3
RTECS號QQ4495249
毒性chicken,LD50,intramuscular,74ug/kg (0.074mg/kg),Toxicon. Vol. 7, Pg. 89, 1969.
常見問題列表
生物活性
α-Bungarotoxin 是煙堿乙酰膽堿受體 (nAChRs) 的競爭性拮抗劑。α-Bungarotoxin 是一種選擇性 α7 受體 (α7 receptor) 阻滯劑，IC50 為 1.6 nM。體外研究
α-Bungarotoxin binds specifically and with high affinity to the nicotinic acetylcholine receptor and competes with binding of the natural ligand. α-Bungarotoxin (α-BTX), is a potent competitive inhibitors of nicotinic acetylcholine receptor function and is highly toxic due to functional blockade of AcChoRs at the neuromuscular junction.