Host:Rabbit
Target Protein:ACLY
IR:Immunogen Range:C-terminal
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:47
Swiss Prot:P53396
Source:KLH conjugated synthetic peptide derived from human ACLY:C-terminal
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:400-800)
Flow-Cyt(1:200)
ICC(1:50-200)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
本產(chǎn)品僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷使用！
關(guān)鍵字： ACL;ATPCL;Cce;AW538652;CLATP;
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