Product Name：Cilengitide
CAS No.：188968-51-6
Synonyms：cyclo(RGDf-N(Me)V-)；cyclo(arginyl-glycyl-aspartyl-D-phenylalanyl-N-methyl-valyl)；西倫吉肽
Catalog No.：143P15
Brand：HongTide（上海鴻肽生物）
Description：Cilengitide是一條含有 RGD 序列的環(huán)肽。該肽基于體內 αv β3整合素配體，通過綜合運用 環(huán)化、空間篩選和甲基化掃描而得，對αvβ3整合素具有高親和性和選擇性。試驗表明，該肽不僅能較好抑制黑色素瘤和膠質細胞瘤生長，而且與放射治療配合能提高其他腫瘤如頭頸鱗狀細胞瘤的治愈率，具有較好的市場前景和潛力。在多肽合成中，Cilengitide是通過固相多肽合成技術與液相多肽合成技術相結合生產出來的。
Cilengitide is a cyclic peptide containing an RGD sequence. This peptide is based on in vivo α v β 3 integrin ligands were obtained through comprehensive application of cyclization, spatial screening, and methylation scanning α v β 3 integrins have high affinity and selectivity. The experiment shows that this peptide can not only inhibit the growth of melanoma and glioma, but also improve the cure rate of other tumors such as head and neck squamous cell tumor when combined with radiotherapy. It has a good market prospect and potential. In peptide synthesis, Cilengitide is produced by combining solid-phase peptide synthesis technology with liquid-phase peptide synthesis technology.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | cyclo(RGDf-N(Me)V) |
Sequence(3-letter code) | cyclo(Arg-Gly-Asp-D-Phe-N-Me-Val) |
Peptide Structure | 
|
Molecular Formula | C27H40N8O7 |
Molecular Weight | 588.66 |
訂購聯系方式：
上海鴻肽生物科技有限公司
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郵箱：sales1@hongtide.com
關鍵字： 188968-51-6;Cilengitide;西倫吉肽;cyclo(RGDf-N(Me)V-);多肽;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產品研發(fā)、生產、銷售以及技術轉讓為主要業(yè) 務科技公司。公司現有產品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質量作船， 以服務為帆，為科研服務”的企業(yè)理念，為國內外眾多科研工作者提供了優(yōu)質的服務及產品。