Product Name：PR 39 (porcine)
CAS No.：139637-11-9
Synonyms：抗菌肽PR 39 (porcine)
Catalog No.：218P088
Brand：HongTide（上海鴻肽生物）
Description：PR 39 (porcine)是富含脯氨酸和精氨酸的天然抗菌肽，是一種非競(jìng)爭(zhēng)性，可逆和變構(gòu)的蛋白酶體 (proteasome) 抑制劑多肽，序列中含有39個(gè)氨基酸。PR 39 (porcine)可逆地結(jié)合到蛋白酶體的α7亞基上，并通過泛素-蛋白酶體途徑阻斷 NF-κB抑制劑IκBα的降解。PR 39 (porcine)能刺激小鼠的血管生成，抑制炎癥反應(yīng)并顯著減小心肌梗死面積。
PR 39 (porcine) is a natural antibacterial peptide rich in proline and arginine. It is a non competitive, reversible, and allosteric proteasome inhibitor peptide with a sequence of 39 amino acids. Reversible binding of PR 39 (porcine) to proteasomes α 7 subunits and blocking NF through the ubiquitin proteasome pathway- κ B inhibitor I κ B α Degradation. PR 39 (porcine) can stimulate angiogenesis in mice, inhibit inflammatory reactions, and significantly reduce myocardial infarction area.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP-NH2 |
Sequence(3-letter code) | H-Arg-Arg-Arg-Pro-Arg-Pro-Pro-Tyr-Leu-Pro-Arg-Pro-Arg-Pro-Pro-Pro-Phe-Phe-Pro-Pro-Arg-Leu-Pro-Pro-Arg-Ile-Pro-Pro-Gly-Phe-Pro-Pro-Arg-Phe-Pro-Pro-Arg-Phe-Pro-NH2 |
Peptide Structure | 
|
Molecular Formula | C229H346N70O40 |
Molecular Weight | 4719.73 |
訂購聯(lián)系方式：
上海鴻肽生物科技有限公司
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關(guān)鍵字： 139637-11-9;PR 39 (porcine);抗菌肽PR 39 (porcine);多肽;抗菌肽;
上海鴻肽生物科技有限公司（簡(jiǎn)稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。