Product Name：Ularitide Acetate
CAS No.：118812-69-4；115966-23-9
Synonyms：Urodilatin (human)；Urodilatin CCC/ANP (95-126)；烏拉立肽；烏羅地丁,人類
Catalog No.：177P05
Brand：HongTide（上海鴻肽）
Description：烏拉立肽（烏羅地丁,人類）是32個氨基酸殘基組成的促尿鈉排泄環(huán)肽，序列中含有一對二硫鍵，在一些臨床實(shí)驗(yàn)中已證實(shí)烏拉立肽能夠降低腎臟對尿液的重吸收。同時以烏拉立肽為主要原料的藥物能降低心臟充盈壓力和改善呼吸困難，且對DHF患者的腎臟功能沒有明顯的不良影響。
Ularitide (Urodilatin human) is a cyclic peptide composed of 32 amino acid residues that promote sodium excretion and contains a pair of disulfide bonds in its sequence. In some clinical experiments, it has been confirmed that Ularitide can reduce renal reabsorption of urine. At the same time, drugs using urethane as the main raw material can reduce cardiac filling pressure and improve dyspnea, and have no significant adverse effects on renal function in patients with DHF.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | TAPRSLRRSSCFGGRMDRIGAQSGLGCNSFRY(Disulfide bridge Cys11-Cys27) |
Sequence(3-letter code) | H-Thr-Ala-Pro-Arg-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH(Disulfide bridge Cys11-Cys27) |
Peptide Structure | 
|
Molecular Formula | C145H234N52O44S3 |
Molecular Weight | 3505.97 |
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上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。