中文名稱

10（11）-EpDPA

英文名字

10(11)-EpDPA

供應(yīng)商

開曼生物

產(chǎn)品貨號(hào)

10471-25

產(chǎn)品報(bào)價(jià)

￥539/25ug

產(chǎn)品說明書

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購買方式

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產(chǎn)品新聞

背景資料

Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. 10(11)-EpDPA is a docosahexaenoic acid (DHA; Item No. 90310) epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 μM.{29509,29508} 10(11)-EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in inflammatory and neuropathic pain models and to potently inhibit angiogenesis and tumor growth in in vitro assays.{29509,26641}

產(chǎn)品描述

A DHA epoxygenase metabolite detected in rat brain and spinal cord, as well as human serum, that acts as a substrate for sEH (Km = 5.1 μM); demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models and potently inhibits angiogenesis and tumor growth in in vitro assays

保存建議

建議您在收到開曼生物品牌的10,11 EDP; 10,11-epoxy Docosapentaenoic Acid; 10(11)-EpDPE; 10,11-epoxy DPA (CAS 895127-65-8) (25 ug)產(chǎn)品后置于-20℃保存.

其他

開曼生物向全球科學(xué)工作者提供多研究領(lǐng)域的生化、免疫試劑和分析試劑盒，其產(chǎn)品被廣泛應(yīng)用于腫瘤、氧化氮、神經(jīng)學(xué)、凋亡、氧化性損傷、內(nèi)分泌學(xué)等不同研究領(lǐng)域.開曼生物可提供用于檢測(cè)的特色試劑盒，如：類花生酸類物質(zhì)、游離的生物標(biāo)志、環(huán)核苷、激素及氧化氮等；也提供多種高質(zhì)量試劑，包括：類花生酸類物質(zhì)、氧化氮試劑及許多相關(guān)脂質(zhì)、脂肪酸、酶和抗體.作為開曼生物在中國(guó)的區(qū)域總代理，艾美捷科技有限公司將為中國(guó)客戶提供最全面的開曼生物產(chǎn)品以及客戶訂制化服務(wù).