中文名稱:Anti NINJ1 Antibody (PHN29901), NINJ1 -人神經(jīng)損傷誘導(dǎo)蛋白1-Protein 1,精品蛋白抗體試劑盒
一 、產(chǎn)品推薦
Recombinant Human NINJ1 Protein, N-GST & C-His (YHN29901)
Recombinant Mouse NINJ1 Protein, N-GST & C-His (YMN29901)
Anti-Human NINJ1 Polyclonal Antibody (PHN29901)
Anti-Mouse NINJ1 Polyclonal Antibody (PMN29901)
NINJ1 ELISA kit
......
二、產(chǎn)品描述
Ninjurin-1,也稱為NINJ1,是跨膜(TM)蛋白Ninjurin家族的成員。它在CD19(+)、CD10(+)B細(xì)胞祖細(xì)胞中表達(dá),在B系急性淋巴細(xì)胞白血病細(xì)胞中表達(dá)水平更高。Ninjurin-1也在其他一些成人和胚胎組織中表達(dá),主要在上皮細(xì)胞中表達(dá)。軸切后,其表達(dá)在遠(yuǎn)端神經(jīng)節(jié)段周圍的神經(jīng)元和雪旺細(xì)胞中上調(diào)。ninjurin-1表達(dá)上調(diào)已被確定為B系急性淋巴細(xì)胞白血病中微小殘留病灶的標(biāo)志物。它在體外介導(dǎo)同性粘附并促進(jìn)背根神經(jīng)節(jié)神經(jīng)元的神經(jīng)突延伸。已發(fā)現(xiàn)Ninjurin-1在肝細(xì)胞癌患者的肝組織中顯示出高表達(dá)水平,這似乎與肝硬化和慢性病毒性肝炎病例有關(guān)。據(jù)報(bào)道,NINJURIN增加人肝癌細(xì)胞中p21的表達(dá)并誘導(dǎo)細(xì)胞衰老。
二 、產(chǎn)品詳情
0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300.
Ninjurin-1, Nerve injury-induced protein 1, Secreted ninjurin-1, Soluble ninjurin-1, NINJ1
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
三、 已發(fā)表文獻(xiàn)
NINJ1 mediates plasma membrane rupture during lytic cell death. PMID: 33472215
NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks. PMID: 38614101
NINJ1 Regulates Platelet Activation and PANoptosis in Septic Disseminated Intravascular Coagulation. PMID: 36835580
NINJ1 induces plasma membrane rupture and release of damage-associated molecular pattern molecules during ferroptosis. PMID: 38396301
NINJ1, rupturing swollen membranes for cataclysmic cell lysis. PMID: 33798414
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