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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Cell Cycle>CDK inhibitors>XL413
XL413
  • XL413

XL413

Price Get Latest Price
Package 200kg
Min. Order: 20kg
Supply Ability: 20 tons
Update Time: 2024-10-29

Product Details

Product Name: XL413 CAS No.: 1169562-71-3
Min. Order: 20kg Purity: 99%
Supply Ability: 20 tons Release date: 2024/10/29

1169562-71-3 - Physico-chemical Properties

Molecular FormulaC14H13Cl2N3O2
Molar Mass326.17792
Appearancepowder
Colorwhite to beige
Storage Condition-20°C
In vitro studyIn MDA-MB-231T and Colo-205 cell lines, XL413 inhibits MCM2 cdc7-specific phosphorylation. XL413 also inhibits cell proliferation in Colo-205 cells, reduces cell viability, and elicits caspase 3/7 activity. In addition, XL413 causes S-phase progression to be altered, which subsequently causes apoptosis.
In vivo studyIn the Colo-205 xenograft model, XL413, at a dose of 3 mg/kg, inhibited 70% of the phosphorylated MCM2 and caused significant tumor growth regression at a dose of 100 mg/kg.


Company Profile Introduction

Qingdao RENAS Polymer Material Co., Ltd. is located in E.T.D.Z of Qingdao China, it is one integrated company, devoted to environmental protection and low carbon energy, new materials introducing, research and development, which aims to offer the best quality products and service to the domestic and foreign markets. We maintain a good partnership with many word famous chemical manufacturers. Integrated of advanced products and technology of domestic and foreign manufacturers, we could customize the products matching scheme for various industries customers, and offer the comprehensive solution to customers. We have unique technology and product advantages, especial in the field of rubber additive, acrylic monomer, solvent, pharmaceutical intermediates and ink coating resin. We have a professional management, business and technical team, and have passed the ISO9001 system certification. We have passed the fast response ability and reliable product quality. With the mission of "steady development and dedication to China", we adhere to the business philosophy of "the interests of users are our most fundamental interests, and the needs of users are our needs". Through concept innovation, management innovation, technical innovation, market innovation, and product innovation, Strive to make the company an excellent supplier in the field of global chemical materials. We welcome friends all over the world to visit and negotiate with us. We sincerely hope to expand our trade and cooperation based on mutual benefits and realize the mutual prosperity and development.

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