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Postion:Product Catalog >Biochemical Engineering>Nucleoside drugs>Nucleoside Intermediates>Uridine triacetate
Uridine triacetate
  • Uridine triacetate

Uridine triacetate NEW

Price $30 $39 $55
Package 50mg 100mg 200mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Uridine triacetate CAS No.: 4105-38-8
Purity: 99.94% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameUridine triacetate
DescriptionUridine triacetate (RG 2133 triacetate) (Tri-O-acetyl uridine), an orally active prodrug of uridine, is efficiently absorbed in the gut and swiftly deacetylated in the circulation to release free uridine. It is utilized in the research of 5-fluorouracil (5-FU) and capecitabine toxicity, particularly targeting early-onset cardiac or central nervous system (CNS) complications.
In vitroUridine triacetate inhibits [3H]uridine uptake in ENT1 and ENT2 overexpressed HeLa cells, with IC50s of 28.4 μM and 228.4 μM respectively[4].
In vivoUridine triacetate (2 g/kg, oral gavage, every 8 h for 15 total doses) improves survival and reduces toxicity in 5-FU overdose and DPD deficiency mice[3].
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationH2O : Insoluble
DMSO : 90 mg/mL (243 mM)
KeywordsRG 2133 Triacetate | Uridine Triacetate | RG2133 Triacetate | Uridine | RG-2133 Triacetate
Related Compound LibrariesFDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Approved Drug Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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