RORγt Inverse agonist 6 NEW
Price | $94 | $238 | $353 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-11 |
Product Details
Product Name: RORγt Inverse agonist 6 | CAS No.: 1887161-80-9 |
Purity: 98.65% | Supply Ability: 10g |
Release date: 2024/11/11 |
Product Introduction
Bioactivity
名稱 | RORγt Inverse agonist 6 |
描述 | RORγt Inverse agonist 6 is an agonist of RORγt inverse. RORγt Inverse agonist 6 can be used in research on Th17-driven autoimmune diseases. |
體內(nèi)活性 | RORγt Inverse agonist 6 (30 mg/kg; p.o.) inhibits the expression level of IL-17A by 59% compared to the vehicle after the oral administration at the tested dose. RORγt Inverse agonist 6 suppresses IL-17A gene expression by IL-23 stimulation in a mouse pharmacodynamics model. RORγt Inverse agonist 6 (1 mg/kg; p.o.) exhibits improved drug exposure with AUC of 1289 ng h/mL[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 45 mg/mL (79.64 mM), Sonication is recommended. |
關(guān)鍵字 | RORγt Inverse agonist-6 | RORγt Inverse agonist6 | RORγt Inverse agonist 6 | RORrt Inverse agonist 6 | RORgammat Inverse agonist 6 | ROR | RAR-related orphan receptor | Inhibitor | inhibit |
相關(guān)產(chǎn)品 | S18-000003 | Cedirogant | T0901317 | GSK2981278 | Nobiletin | XY101 | Cholesterol | AZD-0284 | Melatonin | SR2211 | Cabozantinib hydrochloride | ML 209 |
相關(guān)庫 | 核受體化合物庫 | 經(jīng)典已知活性庫 | 激酶抑制劑庫 | 代謝化合物庫 | 免疫/炎癥分子化合物庫 | 已知活性化合物庫 | 共價抑制劑庫 | 轉(zhuǎn)錄因子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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