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Postion:Product Catalog >RORγt inverse agonist 13
RORγt inverse agonist 13
  • RORγt inverse agonist 13

RORγt inverse agonist 13 NEW

Price $48 $118 $188
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-06

Product Details

Product Name: RORγt inverse agonist 13 CAS No.: 2170477-75-3
Purity: 99% Supply Ability: 10g
Release date: 2024/11/06

Product Introduction

Bioactivity

名稱RORγt inverse agonist 13
描述RORγt inverse agonist 13 (Compound 3i) is a potent, orally active, and selective inverse agonist for RORγt with an IC50 of 63.8 nM, exhibiting improved drug-like properties[1].
體外活性RORγt inverse agonist 13 (Compound 3i) demonstrates 76% inhibition at 0.3 μM in the Th17 cell differentiation assay[1].
體內(nèi)活性RORγt inverse agonist 13 (Compound 3i, 25 mg/kg, orally, twice daily) demonstrates an excellent in vivo PK profile and good efficacy in an IMQ-induced psoriasis mouse model[1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 10 mg/mL (19.48 mM), Sonication is recommended.
關(guān)鍵字ROR | RORγt inverse agonist-13 | RAR-related orphan receptor | inhibit | RORγt inverse agonist13 | RORrt inverse agonist 13 | Inhibitor | RORγt inverse agonist 13 | RORgammat inverse agonist 13
相關(guān)產(chǎn)品S18-000003 | T0901317 | GSK2981278 | Nobiletin | XY101 | Cholesterol | AZD-0284 | Melatonin | SR2211 | Cabozantinib hydrochloride | RORγt Inverse agonist 6 | ML 209
相關(guān)庫核受體化合物庫 | 經(jīng)典已知活性庫 | 激酶抑制劑庫 | 口服活性化合物庫 | 代謝化合物庫 | 已知活性化合物庫 | 共價抑制劑庫 | 轉(zhuǎn)錄因子庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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