Pyridoxal phosphate NEW
| Price | $42 | $44 |
| Package | 100mg | 200mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: Pyridoxal phosphate | CAS No.: 54-47-7 |
| Purity: 99.81% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | Pyridoxal phosphate |
| 描述 | Pyridoxal phosphate (Vitamin B6 phosphate) is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction. |
| 體外活性 | Pyridoxal phosphate results in an immediate reduction in the rate of DNA synthesis. Pyridoxal 5′-phosphate severely inhibits the DNA Polymerase and RNase H. Conjugation to pyridoxal phosphate fully inhibits NEIL2. Pyridoxal phosphate-conjugated NEIL2 shows much lower activity than the intact enzyme over a wide range of enzyme/substrate ratios. After Pyridoxal phosphate conjugation, the ability of NEIL2 to bind the THF-ligand is completely lost. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 50 mg/mL (202.31 mM) H2O : 20.23 mM |
| 關鍵字 | Pyridoxal | Pyridoxal phosphate | Pyridoxyl | Reverse Transcriptase | inhibit | Vitamin B6 Phosphate | Pyridoxyl Phosphate | Inhibitor | Pyridoxal Phosphate | Endogenous Metabolite |
| 相關庫 | 經(jīng)典已知活性庫 | 藥物功能重定位化合物庫 | 抗病毒庫 | 天然產(chǎn)物庫 | 抑制劑庫 | 化妝品成分化合物庫 | 人內(nèi)源代謝化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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