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Postion:Product Catalog >PQCA
PQCA
  • PQCA

PQCA NEW

Price $79 $196 $337
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-13

Product Details

Product Name: PQCA CAS No.: 1144504-35-7
Purity: 98.95% Supply Ability: 10g
Release date: 2024/11/13

Product Introduction

Bioactivity

名稱PQCA
描述PQCA is a muscarinic M1 receptor-positive allosteric regulator, which is highly selective and effective. PQCA exhibited EC50 values of 49 nM in rhesus monkey and 135 nM in human M1 receptors, but showed no activity against other muscarinic receptors. PQCA is a potential compound for reducing cognitive deficits associated with Alzheimer's disease.
體內活性In male rhesus monkeys, oral administration of PQCA (3-30 mg/kg) effectively mitigates the cognitive impairments induced by scopolamine in both the paired-associates learning (PAL) and the continuous performance task (CPT). Scopolamine-induced blockade of muscarinic signaling results in significant deficits in performance on both tasks. [1]
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : <1 mg/mL (insoluble or slightly soluble), Sonication and heating to 80℃ are recommended.
關鍵字PQCA
相關產(chǎn)品Adiphenine hydrochloride | Nanofin | Arecoline hydrobromide | Forskolin | Pilocarpine Hydrochloride | CLOZAPINE N-OXIDE | Pilocarpine nitrate | Ribavirin | Adenine | Amitriptyline hydrochloride | Choline chloride | Propoxur
相關庫神經(jīng)退行性疾病化合物庫 | 經(jīng)典已知活性庫 | 神經(jīng)信號分子庫 | 膜蛋白靶向化合物庫 | 神經(jīng)遞質受體化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Recommended supplier

Product name Price   Suppliers Update time
$79.00/1mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-13
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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