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LY 303511 hydrochloride NEW
Price | $33 | $76 | $128 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-17 |
Product Details
Product Name: LY 303511 hydrochloride | CAS No.: 2070014-90-1 |
Purity: 97.44% | Supply Ability: 10g |
Release date: 2024/11/17 |
Product Introduction
Bioactivity
名稱 | LY 303511 hydrochloride |
描述 | LY 303511 hydrochloride is a potent mTOR inhibitor |
體外活性 | LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via hydrogen peroxide-mediated mitogen-activated protein kinase activation and up-regulation of death receptors. LY303511 amplifies TRAIL-induced apoptosis in tumor cells by enhancing DR5 oligomerization, DISC assembly, and mitochondrial permeabilization. LY303511 acts via phosphatidylinositol 3-kinase-independent pathways to inhibit cell proliferation via mammalian target of rapamycin (mTOR)- and non-mTOR-dependent mechanisms. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 50 mg/mL (145.85 mM) |
關(guān)鍵字 | TNFR | LY-303511 | LY 303511 Hydrochloride | TNF Receptor | inhibit | LY 303511 | LY 303511 hydrochloride | Tumor Necrosis Factor Receptor | LY-303511 Hydrochloride | Inhibitor | LY303511 Hydrochloride | Potassium Channel | LY303511 | KcsA |
相關(guān)產(chǎn)品 | Minoxidil sulfate | Acetylcysteine | Tetraethylammonium bromide | Glucosamine | Halothane | Thalidomide | Apremilast | Lenalidomide | Cloperastine hydrochloride | Fisetin | 2,2,2-Trichloroethanol | Indapamide |
相關(guān)庫 | 抗肺癌化合物庫 | 疼痛相關(guān)化合物庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 激酶抑制劑庫 | 抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 離子通道庫 | 氧化還原化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
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