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Postion:Product Catalog >LY 456236 hydrochloride
LY 456236 hydrochloride
  • LY 456236 hydrochloride

LY 456236 hydrochloride NEW

Price $35 $81 $129
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: LY 456236 hydrochloride CAS No.: 338736-46-2
Purity: 99.89% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameLY 456236 hydrochloride
DescriptionLY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM. LY456236 has selective, non-competitive and oral activity, and can inhibit the hydrolysis of inositol phosphate with IC50 of 0.145 μM. LY 456236 hydrochloride inhibited EGFR with IC50 of 0.91 μM.
In vitroLY456236 (2 μM; 30 min) reduces the proliferation of DHPG-stimulated OCCM-30 cells.[1]
In vivoLY456236 exhibits anticonvulsant effects in mice (3-100 mg/kg; i.p.; once) and rats (10-60 mg/kg; oral; once).[2]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 225.0 mg/mL (708.1 mM), Sonication and heating to 60℃ are recommended.
KeywordsLY 456236 Hydrochloride | LY-456236 Hydrochloride | MPMQ Hydrochloride | LY456236 Hydrochloride
Inhibitors RelatedOsimertinib | Lidocaine Hydrochloride hydrate | Lapatinib | Evans blue | Erlotinib hydrochloride | Erlotinib | Neratinib | L-Glutamic acid monosodium salt | Chalcone | Genistein | Gefitinib | O-Phospho-L-serine
Related Compound LibrariesBioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Neuroprotective Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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