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Postion:Product Catalog >GSK3368715 dihydrochloride
GSK3368715 dihydrochloride
  • GSK3368715 dihydrochloride

GSK3368715 dihydrochloride NEW

Price $56
Package 1mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-11

Product Details

Product Name: GSK3368715 dihydrochloride CAS No.: 1628925-77-8
Purity: 99.66% Supply Ability: 10g
Release date: 2024/11/11

Product Introduction

Bioactivity

名稱GSK3368715 dihydrochloride
描述GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active and potent inhibitor of type I protein arginine methyltransferases (PRMTs), including PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8. It exhibits anticancer and antitumor activity and can be used to study advanced solid tumors.
體外活性In the majority of 249 cancer cell lines representing 12 tumor types, GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) exhibits 50% or more growth inhibition relative to DMSO-treated cells[1].
體內(nèi)活性GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) markedly inhibits the growth of BxPC3 xenografts at all tested doses, achieving tumor growth reductions of 78% and 97% at 150 mg/kg and 300 mg/kg, respectively[1].
存儲(chǔ)條件store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度H2O : 100 mg/mL (227.55 mM), Sonication is recommended.
DMSO : 100 mg/mL (227.55 mM), Sonication is recommended.
關(guān)鍵字GSK 3368715 | GSK-3368715 Dihydrochloride | EPZ-019997 | EPZ 019997 Dihydrochloride | GSK-3368715 | GSK3368715 Dihydrochloride | EPZ 019997 | EPZ019997 | EPZ-019997 Dihydrochloride | GSK 3368715 Dihydrochloride | GSK3368715
相關(guān)產(chǎn)品BIX-01294 trihydrochloride | Tazemetostat | Piribedil | XY1 | UNC 0631 | GSK126 | EPZ015666 | AMI-1 free acid | MS37452 | MRTX-1719

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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