GSK3368715 dihydrochloride NEW
Price | $56 |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-11 |
Product Details
Product Name: GSK3368715 dihydrochloride | CAS No.: 1628925-77-8 |
Purity: 99.66% | Supply Ability: 10g |
Release date: 2024/11/11 |
Product Introduction
Bioactivity
名稱 | GSK3368715 dihydrochloride |
描述 | GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is an orally active and potent inhibitor of type I protein arginine methyltransferases (PRMTs), including PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8. It exhibits anticancer and antitumor activity and can be used to study advanced solid tumors. |
體外活性 | In the majority of 249 cancer cell lines representing 12 tumor types, GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) exhibits 50% or more growth inhibition relative to DMSO-treated cells[1]. |
體內(nèi)活性 | GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) markedly inhibits the growth of BxPC3 xenografts at all tested doses, achieving tumor growth reductions of 78% and 97% at 150 mg/kg and 300 mg/kg, respectively[1]. |
存儲條件 | store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | H2O : 100 mg/mL (227.55 mM), Sonication is recommended. DMSO : 100 mg/mL (227.55 mM), Sonication is recommended. |
關(guān)鍵字 | GSK 3368715 | GSK-3368715 Dihydrochloride | EPZ-019997 | EPZ 019997 Dihydrochloride | GSK-3368715 | GSK3368715 Dihydrochloride | EPZ 019997 | EPZ019997 | EPZ-019997 Dihydrochloride | GSK 3368715 Dihydrochloride | GSK3368715 |
相關(guān)產(chǎn)品 | BIX-01294 trihydrochloride | Tazemetostat | Piribedil | XY1 | UNC 0631 | GSK126 | EPZ015666 | AMI-1 free acid | MS37452 | MRTX-1719 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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