Gardiquimod NEW
Price | $30 | $43 | $68 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-13 |
Product Details
Product Name: Gardiquimod | CAS No.: 1020412-43-4 |
Purity: 98.02% | Supply Ability: 10g |
Release date: 2024/11/13 |
Product Introduction
Bioactivity
名稱 | Gardiquimod |
描述 | Gardiquimod could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells. Gardiquimod is an imidazoquinoline analog and is a TLR7/8 agonist. When used at concentrations below 10?μM, Gardiquimod specifically activates TLR7. |
體外活性 | Administration of 6-60?μM Gardiquimod obviously inhibits HIV-1 reverse transcriptase cDNA synthesis[1]. |
體內(nèi)活性 | Gardiquimod (1 mg/kg per mouse; i.p.; daily for 7 days) in combination with Dendritic cells (DCs) enhance the anti-tumor effects of NK cells[2]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 45 mg/mL (143.59 mM), Sonication is recommended. DMF : 18 mg/mL (57.43 mM) |
關(guān)鍵字 | HIV-1 | Gardiquimod | HepG2 | Toll-like Receptor (TLR) | Inhibitor | PBMCs | inhibit | HIV | cells | peripheral | macrophages | blood | liver | carcinoma | Human immunodeficiency virus | mononuclear |
相關(guān)產(chǎn)品 | Stavudine | 5-Fluorouracil | Emtricitabine | Kaempferol | Dolutegravir intermediate-1 | Dextran sulfate sodium salt (MW 4500-5500) | Hydroxychloroquine | Lamivudine | Chloroquine phosphate | Chloranil | Decanedioic acid | Tenofovir |
相關(guān)庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 細(xì)胞焦亡化合物庫 | 抗病毒庫 | 腫瘤免疫治療小分子化合物庫 | 已知活性化合物庫 | 人代謝物化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Product name | Price | Suppliers | Update time | |
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$49.00/2mg |
VIP3Y
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TargetMol Chemicals Inc.
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2024-10-23 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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