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Postion:Product Catalog >gardiquimod TFA salt
gardiquimod TFA salt
  • gardiquimod TFA salt

gardiquimod TFA salt NEW

Price $49
Package 2mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: gardiquimod TFA salt CAS No.: 1159840-61-5
Supply Ability: 10g Release date: 2024/11/19

Product Introduction

Bioactivity

Namegardiquimod TFA salt
DescriptionGardiquimod diTFA, an imidazoquinoline analog and TLR7/8 agonist, inhibits HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs), and specifically activates TLR7 at concentrations below 10 μM. As an immune system modifier and reverse transcriptase inhibitor, it serves as a novel therapeutic agent to block systemic and mucosal transmission of HIV-1.[1][2]
In vitroGardiquimod diTFA (6-60 μM ) significantly inhibits HIV-1 reverse transcriptase to synthesis of cDNA [1].
In vivoGardiquimod, when administered intraperitoneally at a dosage of 1 mg/kg per mouse daily for 7 days, significantly augmented the anti-tumor effects of natural killer (NK) cells in conjunction with dendritic cells (DCs) on human HepG2 liver carcinoma xenografts in male athymic nude mice (Balb-nu/nu, 5 weeks old). This regimen notably suppressed the growth of the carcinoma xenografts, demonstrating the potential of Gardiquimod as a powerful adjunct in cancer immunotherapy strategies.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Keywordsgardiquimod TFA salt | gardiquimod TFA

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

Recommended supplier

Product name Price   Suppliers Update time
$30.00/1mg
VIP5Y
TargetMol Chemicals Inc.
2024-11-19
$0.00/50mg
VIP1Y
TargetMol Chemicals Inc.
2024-10-28
$0.00/1kg
VIP2Y
Sichuan HongRi Pharma-Tech Co.,Ltd
2024-01-18
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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