EGFR-IN-11 NEW
| Price | $79 | $196 | $337 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-13 |
Product Details
| Product Name: EGFR-IN-11 | CAS No.: 2463200-44-2 |
| Purity: 99.37% | Supply Ability: 10g |
| Release date: 2024/11/13 |
Product Introduction
Bioactivity
| 名稱 | EGFR-IN-11 |
| 描述 | EGFR-IN-11 is a selective inhibitor of EGFR-tyrosine kinase and induces cell apoptosis. EGFR-IN-11 inhibits triple mutant EGFRL858R/T790M/C797S with an IC50 of 18 nM and arrests cell cycle at G0/G1. |
| 體外活性 | EGFR-IN-11 (0.1 nM-10 μM) shows anti-proliferation with IC50s of 0.88 nM, 0.20 μM and 2.91 μM for HCC827, H1975 and A549 cells. EGFR-IN-11 (10nM-10 μM) suppresses the phosphorylation of EGFR in a concentration-dependent manner in the HCC827, H1975 and A549 cells[1]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 112.5 mg/mL (196.1 mM ), Sonication is recommended. |
| 關(guān)鍵字 | EGFR-IN-11 | EGFRIN11 | EGFR IN 11 |
| 相關(guān)產(chǎn)品 | Osimertinib | Lidocaine Hydrochloride hydrate | Lapatinib | Afatinib Dimaleate | Erlotinib hydrochloride | Erlotinib | Neratinib | Chalcone | Osimertinib mesylate | Genistein | Khellin | Gefitinib |
| 相關(guān)庫(kù) | 細(xì)胞凋亡化合物庫(kù) | 抗結(jié)直腸癌化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 膜蛋白靶向化合物庫(kù) | 酪氨酸激酶分子庫(kù) | 激酶抑制劑庫(kù) | 抗乳腺癌化合物庫(kù) | JAK-STAT 化合物庫(kù) | 抑制劑庫(kù) | 干細(xì)胞分化化合物庫(kù) | 免疫/炎癥分子化合物庫(kù) | 已知活性化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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