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Postion:Product Catalog > Mutated EGFR-IN-1
	Mutated EGFR-IN-1
  • 	Mutated EGFR-IN-1
  • 	Mutated EGFR-IN-1

Mutated EGFR-IN-1 NEW

Price $5 $0.1
Package 1KG 1000KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-04-09

Product Details

Product Name: Mutated EGFR-IN-1 CAS No.: 1421372-66-8
Min. Order: 1KG Purity: 98%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/04/09
Lead time: In stock, ready for shipment Packaging: bag/bottle/drum/IBC
Delivery: By express, by air, by sea Delivery: Manufacturer, advantage product
COA, MSDS: Manufacturer, advantage product Name: Tina

 1. Materials information

Names

NameN1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)benzene-1,2,4-triamine
SynonymMore Synonyms

 Mutated EGFR-IN-1 Biological Activity

DescriptionMutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant and T790M resistance mutant.IC50 value:Target: Mutated EGFR inhibitorMore information can be found in Patent WO 2013014448 A1.2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer.
Related Catalog
Research Areas >> Cancer
Target

EGFRL858R

EGFRExon 19 deletion/T790M

EGFRT790M

References

[1]. Patent WO 2013014448 A1. 2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer.

 Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point676.5±65.0 °C at 760 mmHg
Molecular FormulaC25H31N7O
Molecular Weight445.560
Flash Point363.0±34.3 °C
Exact Mass445.259003
PSA84.47000
LogP2.17
Vapour Pressure0.0±2.1 mmHg at 25°C
Index of Refraction1.635
Storage condition2-8℃

 Synonyms

Mutated EGFR-IN-1
AZD9291 intermediate 3
1,2,4-Benzenetriamine, N-[2-(dimethylamino)ethyl]-5-methoxy-N-methyl-N-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-
N-[2-(Dimethylamino)ethyl]-5-methoxy-N-methyl-N-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine
N1-[2-(diMethylaMino)ethyl]-5-Methoxy-N 1-Methyl-N4-[4-(1-Methyl-1H-indol-3-yl)-2-pyriMidinyl]benzene-1,2,4-triamine

2. Packaging of materials


  • For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

  • For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                             Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping & Delivery

  • By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

Article illustration


  • By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

Article illustration


  • By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address: Tina@fdachem.com

Mob: 86 13213167925

WhatsApp/Skype/Wechat/LINE: 86 13213167925











Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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