Eflornithine NEW
| Price | $29 |
| Package | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-13 |
Product Details
| Product Name: Eflornithine | CAS No.: 70052-12-9 |
| Purity: 99.44% | Supply Ability: 10g |
| Release date: 2024/11/13 |
Product Introduction
Bioactivity
| 名稱 | Eflornithine |
| 描述 | Eflornithine (DFMO) is a selective and orally available ornithine decarboxylase inhibitor that delays hair overgrowth.Eflornithine is used in the study of African trypanosomiasis, malignant glioma, and sleeping sickness. |
| 體內(nèi)活性 | Eflornithine is the only newly registered molecule for the treatment of human African trypanosomiasis in the past 50 years, mainly serving as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases[1]. In subjects with excessive facial hair, eflornithine 15% cream reduces hair growth more effectively than placebo, with 58% of eflornithine users showing improvement after 24 weeks compared to 34% for placebo[2]. The hair growth inhibitory effect is significantly enhanced when eflornithine cream is applied to mouse skin pretreated with microneedles[3]. In coarctation hypertensive rats, eflornithine treatment normalizes contractile responses to KCI and norepinephrine and acetylcholine-induced relaxations after 14 days[4]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | H2O : 50 mg/mL (274.47 mM), Sonication and heating are recommended. |
| 相關(guān)產(chǎn)品 | Hydroxychloroquine | Doxycycline |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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| $1520.00/25mg |
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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