CDDO-3P-Im NEW
| Price | $96 | $198 | $328 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-12 |
Product Details
| Product Name: CDDO-3P-Im | CAS No.: 1883650-95-0 |
| Purity: 97.13% | Supply Ability: 10g |
| Release date: 2024/11/12 |
Product Introduction
Bioactivity
| 名稱 | CDDO-3P-Im |
| 描述 | CDDO-3P-Im is an orally active inhibitor of necroptosis with chemopreventive effects. CDDO-3P-Im can be used in studies about ischemia/reperfusion. |
| 體外活性 | CDDO-3P-Im (30 nM) induces differentiation of U937 cells. In RAW264.7 cells, CDDO-3P-Im suppresses NO production (IC50 = 4.3 nM)[1]. |
| 體內(nèi)活性 | CDDO-3P-Im reduces the size and the severity of the lung tumors in mouse lung cancer models. In A/J mice, CDDO-3P-Im (50-200 mg/kg; diet) decreases the number, size, and severity of tumors. CDDO-3P-Im significantly elevates heme oxygenase-1 and quinone reductase mRNA and protein levels in various mouse tissues[1]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 225 mg/mL (363.6 mM), Sonication is recommended. |
| 關(guān)鍵字 | CDDO 3P Im | CDDO3PIm | CDDO-3P-Im |
| 相關(guān)產(chǎn)品 | MLKL-IN-6 | Cholicamideβ | Necrostatin-5 | RIP1 kinase inhibitor 8 | Necroptosis-IN-3 | Anticancer agent 146 | TP4 (Nile tilapia piscidin) |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 抑制劑庫 | 已知活性化合物庫 | 共價(jià)抑制劑庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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